Recombinant Human DNMT2, His-tagged

Cat.No. : DNMT2-12109H
Product Overview : Recombinant Human DNMT2 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Availability April 02, 2025
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Species : Human
Source : E.coli
Tag : His
Protein Length : 1-391a.a.
Description : This gene encodes a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. This enzyme also possesses residual DNA-(cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conserved in its function among taxa.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name TRDMT1 tRNA aspartic acid methyltransferase 1 [ Homo sapiens ]
Official Symbol TRDMT1
Synonyms TRDMT1; tRNA aspartic acid methyltransferase 1; DNA (cytosine 5 ) methyltransferase 2 , DNMT2; tRNA (cytosine(38)-C(5))-methyltransferase; RNMT1; DNA methyltransferase-2; DNA MTase homolog HsaIIP; tRNA (cytosine-5-)-methyltransferase; DNA (cytosine-5)-methyltransferase-like protein 2; DMNT2; DNMT2; PUMET; MHSAIIP;
Gene ID 1787
mRNA Refseq NM_004412
Protein Refseq NP_004403
MIM 602478
UniProt ID O14717
Chromosome Location 10p15.1
Function DNA (cytosine-5-)-methyltransferase activity; DNA binding; RNA binding; methyltransferase activity; transferase activity;

Not For Human Consumption!

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