Recombinant Human DNMT1 protein, GST-tagged

• Cat.No.: DNMT1-72H
• Product Overview: Recombinant Human DNMT1 protein, fused with N-terminal GST tag, was expressed in insect cell.

Specification

• Description: DNA (cytosine-5)-methyltransferase 1 (DNMT1) methylates CpG residues, preferentially methylating hemimethylated DNA to maintain the methylation pattern in the new strand of replicated DNA.
• Source: Insect cell
• Species: Human
• Tag: GST
• Form: 20 mM Tris/HCl pH 7.5, 120 mM NaCl, 1 mM TCEP, 10% glycerol (v/v).
• Molecular Mass: 209.0 kDa
• Protein length: 2-1632
• Purity: >85% by SDS-PAGE
• Storage: Store at -80°C. Thaw quickly and store on ice before use. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: DNMT1 DNA (cytosine-5-)-methyltransferase 1 [ Homo sapiens ]
• Official Symbol: DNMT1
• Synonyms: DNMT1; DNA (cytosine-5-)-methyltransferase 1; DNMT; DNA (cytosine-5)-methyltransferase 1; CXXC9; MCMT; m.HsaI; DNA MTase HsaI; CXXC finger protein 9; DNA methyltransferase 1; DNA methyltransferase HsaI; CXXC-type zinc finger protein 9; AIM; HSN1E; FLJ16293; MGC104992
• Gene ID: 1786
• mRNA Refseq: NM_001130823
• Protein Refseq: NP_001124295
• MIM: 126375
• UniProt ID: P26358
• Chromosome Location: 19p13.2
• Pathway: Cysteine and methionine metabolism, organism-specific biosystem; Cysteine and methionine metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; Methionine degradation, organism-specific biosystem; Methionine degradation, conserv
• Function: DNA (cytosine-5-)-methyltransferase activity; DNA binding; DNA-methyltransferase activity; metal ion binding; protein binding; transcription factor binding; transferase activity; zinc ion binding