Recombinant Human DNER, Fc-tagged

• Cat.No.: DNER-28368TH
• Product Overview: Recombinant fragment of Human DNER fused at the C terminus to the Fc portion of Human IgG1; mwt 120 kDa by SDS Page.

Specification

• Description: Delta and Notch-like epidermal growth factor-related receptor is a protein that in humans is encoded by the DNER gene.
• Protein length: 637 amino acids
• Conjugation: Fc
• Molecular Weight: 120.000kDa
• Source: HEK 293 cells
• Tissue specificity: Expressed in brain, spinal cord and adrenal gland.
• Biological activity: Inhibits adipogenesis of 3T3L-1 cells.
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: PBS
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Sequence Similarities: Contains 10 EGF-like domains.Contains 1 follistatin-like domain.

Gene Information

• Gene Name: DNER delta/notch-like EGF repeat containing [ Homo sapiens ]
• Official Symbol: DNER
• Synonyms: DNER; delta/notch-like EGF repeat containing; delta and Notch-like epidermal growth factor-related receptor; bet; UNQ26
• Gene ID: 92737
• mRNA Refseq: NM_139072
• Protein Refseq: NP_620711
• MIM: 607299
• Uniprot ID: Q8NFT8
• Chromosome Location: 2q36.3
• Pathway: Notch signaling pathway, organism-specific biosystem
• Function: Notch binding; calcium ion binding; clathrin binding; protein binding; receptor activity