Recombinant Human DND1, GST-tagged

• Cat.No.: DND1-12100H
• Product Overview: Recombinant Human DND1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene encodes a protein that binds to microRNA-targeting sequences of mRNAs, inhibiting microRNA-mediated repression. Reduced expression of this gene has been implicated in tongue squamous cell carcinoma. Two pseudogenes of this gene are located on the long arm of chromosome 17.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-353a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: DND1 dead end homolog 1 (zebrafish) [ Homo sapiens ]
• Official Symbol: DND1
• Synonyms: DND1; dead end homolog 1 (zebrafish); dead end protein homolog 1; MGC34750; RBMS4; RNA-binding motif, single-stranded-interacting protein 4
• Gene ID: 373863
• mRNA Refseq: NM_194249
• Protein Refseq: NP_919225
• MIM: 609385
• UniProt ID: Q8IYX4
• Chromosome Location: 5q31.3
• Function: AU-rich element binding; NOT miRNA binding; nucleotide binding