Recombinant Human DNALI1, GST-tagged

• Cat.No.: DNALI1-12093H
• Product Overview: Recombinant Human DNALI1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-258a.a.
• Description: This gene is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS). Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: DNALI1 dynein, axonemal, light intermediate chain 1 [ Homo sapiens ]
• Official Symbol: DNALI1
• Synonyms: DNALI1; dynein, axonemal, light intermediate chain 1; dynein, axonemal, light intermediate polypeptide 1; axonemal dynein light intermediate polypeptide 1; dJ423B22.5; dJ423B22.5 (axonemal dynein light chain (hp28)); hp28; inner dynein arm; homolog of clamydomonas; P28; inner dynein arm light chain, axonemal; inner dynein arm, homolog of clamydomonas
• Gene ID: 7802
• mRNA Refseq: NM_003462
• Protein Refseq: NP_003453
• MIM: 602135
• UniProt ID: O14645
• Chromosome Location: 1p35.1
• Pathway: Huntingtons disease, organism-specific biosystem; Huntingtons disease, conserved biosystem
• Function: microtubule motor activity