DNALI1
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Official Full Name
dynein, axonemal, light intermediate chain 1 -
Overview
This gene is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS). Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects. -
Synonyms
DNALI1;dynein, axonemal, light intermediate chain 1;dynein, axonemal, light intermediate polypeptide 1;axonemal dynein light intermediate polypeptide 1;dJ423B22.5;dJ423B22.5 (axonemal dynein light chain (hp28));hp28;inner dynein arm;homolog of clamydomonas;P28;Axonemal dynein light chain (hp28);Axonemal dynein light chain;DNALI 1;Dynein axonemal light intermediate chain 1;Dynein axonemal light intermediate polypeptide 1;Inner dynein arm homolog of clamydomonas;Inner dynein arm light chain axonemal;OTTHUMP00000004400;inner dynein arm light chain, axonemal;inner dynein arm, homolog of clamydomonas
Recombinant Proteins
- Human
- Rat
- Cynomolgus
- Zebrafish
- Mouse
- E.coli
- Mammalian Cells
- Wheat Germ
- E.Coli/Yeast
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
DNALI1 involved in several pathways and played different roles in them. We selected most pathways DNALI1 participated on our site, such as Huntingtons disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with DNALI1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Huntingtons disease | GPX1,NDUFB4,POLR2E,POLR2H,COX5B,EP300,CREB3L1,ATP5G3,ATP5J,SOD1 |
Protein Function
DNALI1 has several biochemical functions, for example, dynein heavy chain binding,microtubule motor activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DNALI1 itself. We selected most functions DNALI1 had, and list some proteins which have the same functions with DNALI1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | RNF115,GRB7,GFI1B,STRA13,TARDBP,MYPOP,LGR4,FAN1,PTPRR,FMNL1 |
| dynein heavy chain binding | DYNC2LI1 |
| microtubule motor activity | KIFC2,KLC3,KLC1A,DYNC1I2,DNHD1,DYNC1I1,DNAH9,KIF15,KIF25,KLC1B |
Interacting Protein
DNALI1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DNALI1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DNALI1.
SIAH1;HTT;PRMT6;EPS8;ABCF3;MED19;Med28;MED29
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