Recombinant Human DNAJC27 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: DNAJC27-4713H
• Product Overview: DNAJC27 MS Standard C13 and N15-labeled recombinant protein (NP_057628) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling.
• Molecular Mass: 30.9 kDa
• AA Sequence: MEANMPKRKEPGRSLRIKVISMGNAEVGKSCIIKRYCEKRFVSKYLATIGIDYGVTKVHVRDREIKVNIFDMAGHPFFYEVRNEFYKDTQGVILVYDVGQKDSFDALDAWLAEMKQELGPHGNMENIIFVVCANKIDCTKHRCVDESEGRLWAESKGFLYFETSAQTGEGINEMFQTFYISIVDLCENGGKRPTTNSSASFTKEQADAIRRIRNSKDSWDMLGVKPGASRDEVNKAYRKLAVLLHPDKCVAPGSEDAFKAVVNARTALLKNIKTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: DNAJC27 DnaJ heat shock protein family (Hsp40) member C27 [ Homo sapiens (human) ]
• Official Symbol: DNAJC27
• Synonyms: DNAJC27; DnaJ (Hsp40) homolog, subfamily C, member 27; rab and DnaJ domain containing, RBJ; dnaJ homolog subfamily C member 27; RabJS; Ras-associated protein Rap1; rab and DnaJ domain-containing protein; RBJ; DKFZp434N211
• Gene ID: 51277
• mRNA Refseq: NM_016544
• Protein Refseq: NP_057628
• MIM: 613527
• UniProt ID: Q9NZQ0