Recombinant Human DNAJC10, GST-tagged

• Cat.No.: DNAJC10-12072H
• Product Overview: Recombinant Human DNAJC10 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene encodes an endoplasmic reticulum co-chaperone which is part of the endoplasmic reticulum-associated degradation complex involved in recognizing and degrading misfolded proteins. The encoded protein reduces incorrect disulfide bonds in misfolded glycoproteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: C-term-104a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 [ Homo sapiens ]
• Official Symbol: DNAJC10
• Synonyms: DNAJC10; DnaJ (Hsp40) homolog, subfamily C, member 10; dnaJ homolog subfamily C member 10; ERdj5; PDIA19; protein disulfide isomerase family A; member 19; MTHr; macrothioredoxin; ER-resident protein ERdj5; protein disulfide isomerase family A, member 19; J-domain-containing protein disulfide isomerase-like protein; JPDI; MGC104194; DKFZp434J1813
• Gene ID: 54431
• mRNA Refseq: NM_018981
• Protein Refseq: NP_061854
• MIM: 607987
• UniProt ID: Q8IXB1
• Chromosome Location: 2q32.1
• Pathway: Protein processing in endoplasmic reticulum, organism-specific biosystem; Protein processing in endoplasmic reticulum, conserved biosystem
• Function: ATPase activator activity; ATPase binding; chaperone binding; disulfide oxidoreductase activity; electron carrier activity; heat shock protein binding; misfolded protein binding; protein binding; protein disulfide oxidoreductase activity; unfolded protein