Recombinant Human DNAJB4 Protein, MYC/DDK-tagged
| Cat.No. : | DNAJB4-2390H |
| Product Overview : | Recombinant Human DNAJB4 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293. |
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| Description : | The protein encoded by this gene is a molecular chaperone, tumor suppressor, and member of the heat shock protein-40 family. The encoded protein binds the cell adhesion protein E-cadherin and targets it to the plasma membrane. This protein also binds incorrectly folded E-cadherin and targets it for endoplasmic reticulum-associated degradation. This gene is a strong tumor suppressor for colorectal carcinoma, and downregulation of it may serve as a good biomarker for predicting patient outcomes. Several transcript variants encoding different isoforms have been found for this gene. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc&DDK |
| Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
| Molecular Mass : | 37.6 kDa |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration : | >50 ug/mL as determined by microplate BCA method |
| Gene Name | DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 [ Homo sapiens ] |
| Official Symbol | DNAJB4 |
| Synonyms | DjB4; DNAJW; HLJ1 |
| Gene ID | 11080 |
| mRNA Refseq | NM_007034 |
| Protein Refseq | NP_008965 |
| MIM | 611327 |
| UniProt ID | Q9UDY4 |
Not For Human Consumption!
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