Recombinant Human DnaJ (Hsp40) Homolog, Subfamily C, Member 12, His-tagged

• Cat.No.: DNAJC12-6948H
• Product Overview: Recombinant human DNAJC12 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Specification

• Description: DNAJC12, is a member of the DnaJ/Hsp40 family. The members of the DnaJ/Hsp40 proteins are highly conserved through evolution, expressed in several tissues and act as co-chaperone regulating protein folding, transport, translational initiation and gene expression. DnaJC12 may play a role in protein folding and export and is thought to be involved in estrogen control and the development of breast cancer.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20 mM Tris-HCl buffer, pH8.0, 10% glycerol, 2mM DTT, 100mM NaCl.
• Molecular Mass: 26.0 kDa (222aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher).
• Protein length: 1-198aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMDAILN YRSEDTEDYY TLLGCDELSS VEQILAEFKV RALECHPDKH PENPKAVETF QKLQKAKEIL TNEESRARYD HWRRSQMSMP FQQWEALNDS VKTSMHWVVR GKKDLMLEES DKTHTTKMEN EECNEQRERK KEELASTAEK TEQKEPKPLE KSVSPQNSDS SGFADVNGWH LRFRWSKDAP SELLRKFRNY EI
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 [ Homo sapiens ]
• Official Symbol: DNAJC12
• Synonyms: DNAJC12; DnaJ (Hsp40) homolog, subfamily C, member 12; dnaJ homolog subfamily C member 12; J domain protein 1; JDP1; j domain-containing protein 1; J domain containing protein 1 (JDP1); RP11-57G10.2
• Gene ID: 56521
• mRNA Refseq: NM_021800
• Protein Refseq: NP_068572
• MIM: 606060
• UniProt ID: Q9UKB3
• Chromosome Location: 10q21.3
• Function: heat shock protein binding; unfolded protein binding