Recombinant Human DNAI2, His-tagged

• Cat.No.: DNAI2-12053H
• Product Overview: Recombinant Human DNAI2 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: C-term-355a.a.
• Description: The protein encoded by this gene belongs to the dynein intermediate chain family, and is part of the dynein complex of respiratory cilia and sperm flagella. Mutations in this gene are associated with primary ciliary dyskinesia type 9. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: DNAI2 dynein, axonemal, intermediate chain 2 [ Homo sapiens ]
• Official Symbol: DNAI2
• Synonyms: DNAI2; dynein, axonemal, intermediate chain 2; dynein, axonemal, intermediate polypeptide 2; dynein intermediate chain 2, axonemal; CILD9; dynein intermediate chain 2
• Gene ID: 64446
• mRNA Refseq: NM_001172810
• Protein Refseq: NP_001166281
• MIM: 605483
• UniProt ID: Q9GZS0
• Chromosome Location: 17q25
• Pathway: Huntingtons disease, organism-specific biosystem; Huntingtons disease, conserved biosystem
• Function: microtubule motor activity