Recombinant Human DNAH11 protein, His & T7-tagged

• Cat.No.: DNAH11-1636H
• Product Overview: Recombinant Human DNAH11 aa. (Pro17~Val299 (Accession # Q96DT5)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His&T7
• Protein Length: Pro17~Val299
• Description: This gene encodes a ciliary outer dynein arm protein and is a member of the dynein heavy chain family. It is a microtubule-dependent motor ATPase and has been reported to be involved in the movement of respiratory cilia. Mutations in this gene have been implicated in causing Kartagener Syndrome (a combination of situs inversus totalis and Primary Ciliary Dyskinesia (PCD), also called Immotile Cilia Syndrome 1 (ICS1)) and male sterility.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 35.7kDa
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Isoelectric Point: 5.2

Gene Information

• Gene Name: DNAH11 dynein axonemal heavy chain 11 [ Homo sapiens (human) ]
• Official Symbol: DNAH11
• Synonyms: DNAH11; dynein axonemal heavy chain 11; CILD7; DNHBL; DPL11; DNAHBL; DNAHC11; dynein heavy chain 11, axonemal; axonemal beta dynein heavy chain 11; axonemal dynein heavy chain 11; ciliary dynein heavy chain 11; dynein, axonemal, heavy polypeptide 11; dynein, ciliary, heavy chain 11
• Gene ID: 8701
• mRNA Refseq: NM_001277115.1
• Protein Refseq: NP_001264044.1
• UniProt ID: Q96DT5