Recombinant Human DLG3 Protein, GST-tagged

• Cat.No.: DLG3-2676H
• Product Overview: Human DLG3 full-length ORF ( NP_066943.2, 1 a.a. - 817 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the membrane-associated guanylate kinase protein family. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked cognitive disability. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 116.7 kDa
• AA Sequence: MHKHQHCCKCPECYEVTRLAALRRL EPPGYGDWQVPDPYGPGGGNGASAG YGGYSSQTLPSQAGATPTPRTKAKL IPTGRDVGPVPPKPVPGKSTPKLNG SGPSWWPECTCTNRDWYEQVNGSDG MFKYEEIVLERGNSGLGFSIAGGID NPHVPDDPGIFITKIIPGGAAAMDG RLGVNDCVLRVNEVDVSEVVHSRAV EALKEAGPVVRLVVRRRQPPPETIM EVNLLKGPKGLGFSIAGGIGNQHIP GDNSIYITKIIEGGAAQKDGRLQIG DRLLAVNNTNLQDVRHEEAVASLKN TSDMVYLKVAKPGSLHLNDMYAPPD YASTFTALADNHISHNSSLGYLGAV ESKVSYPAPPQVPPTRYSPIPRHML AEEDFTREPRKIILHKGSTGLGFNI VGGEDGEGIFVSFILAGGPADLSGE LRRGDRILSVNGVNLRNATHEQAAA ALKRAGQSVTIVAQYRPEEYSRFES KIHDLREQMMNSSMSSGSGSLRTSE KRSLYVRALFDYDRTRDSCLPSQGL SFSYGDILHVINASDDEWWQARLVT PHGESEQIGVIPSKKRVEKKERARL KTVKFHARTGMIESNRDFPGLSDDY YGAKNLKGQEDAILSYEPVTRQEIH YARPVIILGPMKDRVNDDLISEFPH KFGSCVPHTTRPRRDNEVDGQDYHF VVSREQMEKDIQDNKFIEAGQFNDN LYGTSIQSVRAVAERGKHCILDVSG NAIKRLQQAQLYPIAIFIKPKSIEA LMEMNRRQTYEQANKIYDKAMKLEQ EFGEYFTAIVQGDSLEEIYNKIKQI IEDQSGHYIWVPSPEKL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DLG3 discs, large homolog 3 (Drosophila) [ Homo sapiens ]
• Official Symbol: DLG3
• Synonyms: DLG3; discs, large homolog 3 (Drosophila); discs, large homolog 3 (neuroendocrine dlg, Drosophila); disks large homolog 3; KIAA1232; MRX90; NE Dlg; NEDLG; neuroendocrine dlg; SAP 102; SAP102; neuroendocrine-DLG; synapse-associated protein 102; MRX; XLMR
• Gene ID: 1741
• mRNA Refseq: NM_001166278
• Protein Refseq: NP_001159750
• MIM: 300189
• UniProt ID: Q92796