DLG3
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Official Full Name
Dlg3 discs, large homolog 3 (Drosophila) -
Synonyms
DLG3;discs, large homolog 3 (Drosophila);disks large homolog 3;SAP-102;discs large homolog 3;synapse-associated protein 102;Dlgh3;SAP102;mKIAA1232
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- Mammalian cells
- HEK293T
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
- Flag
- Myc&DDK
Involved Pathway
DLG3 involved in several pathways and played different roles in them. We selected most pathways DLG3 participated on our site, such as Activation of Ca-permeable Kainate Receptor,Activation of Kainate Receptors upon glutamate binding,Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with DLG3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ionotropic activity of Kainate Receptors | DLG1L,NCALDA |
| Axon guidance | GNAI1,SCN8A,RHOA,ARPC1B,ACTR2B,RNF8,HBEGF,KBTBD7,SEMA3AA,CLTA |
| Developmental Biology | KIF4A,FGF8B,TRPC4,NR2F2,SIAH2,CNTN1,SPRED3,SEMA4D,EPHB4B,JAK3 |
| L1CAM interactions | CNTN6,NADL1.1,SCN8A,SCN2A,CHL1,SCN4A,KCNQ3,CD24,DCX,EZRA |
| Activation of Kainate Receptors upon glutamate binding | DLG4,GNB5,DLG1L,NCALDA |
| Activation of Ca-permeable Kainate Receptor | DLG4,NCALDA,DLG1L |
| Neuronal System | KCNN4,KCNV1,KCNH8,PPFIA1,CACFD1,SLC18A3A,KCNH6,KCNS2,KCNH6A,KCNK2 |
| Hippo signaling pathway | WNT1,INADL,ID2,SAV1,YWHAB,PPP1CB,STK3,BTRC,FZD8,CCND1 |
Protein Function
DLG3 has several biochemical functions, for example, PDZ domain binding,guanylate kinase activity,ionotropic glutamate receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DLG3 itself. We selected most functions DLG3 had, and list some proteins which have the same functions with DLG3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| guanylate kinase activity | TJP2,CARD11,GUK1A,DLG1,DLG1L,MPP1,DLG4,MPP3,CASK,MPP2 |
| phosphatase binding | CSRNP2,PPP1R35,PPARA,CTSC,DYSFIP1,CNST,SMAD3,CRY1,SMAD2,CRY2 |
| kinase binding | TRADD,PARK2,RASGRP3,HAP1,TAX1BP1,UBQLN1,JAKMIP2,PRKCD,DLG1,PFKL |
| protein C-terminus binding | STIP1,CDC20,SREBF2,MIF4GD,BAIAP2,C11orf60,PEX10,AGO2,AXIN1,YAP1 |
| ubiquitin protein ligase binding | UBE2W,ABI2,KDM4A,UBE2G2,CKB,RELA,PRKAR1A,AXIN2,IKBKE,CUL3A |
| ionotropic glutamate receptor binding | DLG1L,DLG1,FUS,DRD2,CANX,GNAS,CACNG2,DLG4B,SHANK1,SHANK3 |
| PDZ domain binding | ATP2B4,LIN7C,GRIK5,LPAR2,FZD2,SLC26A6,FZD1,ARHGAP29,PDZK1,KIDINS220 |
| protein binding | TRIP10,IGFBP7,COX4I2,NEK3,S100A12,C1orf38,FHL5,PPFIA2,SOS1,MYLK |
| protein phosphatase binding | GNB2L1,VRK3,MET,ANAPC5,FGF19,MAP3K5,ITGA1,MAP2K7,JUPA,SNX3 |
Interacting Protein
DLG3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DLG3 here. Most of them are supplied by our site. Hope this information will be useful for your research of DLG3.
GDA;PPP1CA;KRT34;ABCA1;ANXA1;S100A3;HIST1H2BC;KRT85;CUL2;KRT31;KRT35;KLHDC3;KRT82;CAMK2A
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