Recombinant Human DKK1 Protein, GST-tagged

• Cat.No.: DKK1-2663H
• Product Overview: Human DKK1 full-length ORF ( AAH01539.1, 1 a.a. - 266 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 55.00 kDa
• AA Sequence: MMALGAAGATRVSVAMVAAALGGHP LLGVSATLNSVLNSNAIKNLPPPLG GAAGHPGSAVSAAPGILYPGGNKYQ TIDNYQPYPCAEDEECGTDEYCASP TRGGDAGVQICLACRKRRKRCMRHA MCCPGNYCKNGICVSSDQNHFRGEI EETITESFGNDHSTLDGYSRRTTLS SKMYHTTGQEGSVCLRSSDCASGLC CARHFWSKICKPVLKGGQVCTKHRR KGSHGLEIFQRCYCGEGLSCRIQKD HHQASNSSRLHTCQRH
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DKK1 dickkopf 1 homolog (Xenopus laevis) [ Homo sapiens ]
• Official Symbol: DKK1
• Synonyms: DKK1; dickkopf 1 homolog (Xenopus laevis); dickkopf (Xenopus laevis) homolog 1; dickkopf-related protein 1; DKK 1; SK; hDkk-1; dickkopf-1 like; dickkopf related protein-1; DKK-1
• Gene ID: 22943
• mRNA Refseq: NM_012242
• Protein Refseq: NP_036374
• MIM: 605189
• UniProt ID: O94907