Recombinant Human DGKQ, His-tagged

• Cat.No.: DGKQ-11959H
• Product Overview: Recombinant Human DGKQ protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 595-942a.a.
• Description: The protein encoded by this gene contains three cysteine-rich domains, a proline-rich region, and a pleckstrin homology domain with an overlapping Ras-associating domain. It is localized in the speckle domains of the nucleus, and mediates the regeneration of phosphatidylinositol (PI) from diacylglycerol in the PI-cycle during cell signal transduction.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: DGKQ diacylglycerol kinase, theta 110kDa [ Homo sapiens ]
• Official Symbol: DGKQ
• Synonyms: DGKQ; diacylglycerol kinase, theta 110kDa; DAGK4, diacylglycerol kinase, theta (110kD); diacylglycerol kinase theta; DAGK; DAGK7; DGK-theta; DAG kinase theta; diglyceride kinase theta; DAGK4
• Gene ID: 1609
• mRNA Refseq: NM_001347
• Protein Refseq: NP_001338
• MIM: 601207
• UniProt ID: P52824
• Chromosome Location: 4p16.3
• Pathway: Effects of PIP2 hydrolysis, organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; Glycerolipid metabolism, organism-specific biosystem; Glycerolipid metabolism, conserved biosystem; Glycerophospholipid metabolism, organism-specific biosystem; Glycerophospholipid metabolism, conserved biosystem
• Function: ATP binding; activating transcription factor binding; diacylglycerol kinase activity; kinase binding; metal ion binding; nucleotide binding; phospholipase binding; protein binding; transferase activity