Recombinant Human developmental pluripotency associated 5, His-tagged

• Cat.No.: DPPA5-678H
• Product Overview: DPPA5, 1-116aa Human, His tag, E.coli

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-116 a.a.
• Description: Developmental pluripotency-associated 5 proteins, also known as DPPA5, is a 116 amino acid protein that localizes to the cytoplasm and contains one KH domain. Expressed in embryonic germ (EG), primordial germ (PG) and embryonic stem (ES) cells, DPPA5 plays an important role in the maintenance of ES cell pluripotency and may be necessary for proper embryogenesis. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Recombinant human DPPA5 protein, fused to His-tag at N-terminus, was expressed in E.coli.
• Form: Liquid. In 20mM Phosphate buffer (pH 8.0) containing 10% glycerol
• Molecular Mass: 15.9kDa (139aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMGTLPAR RHIPPWVKVP EDLKDPEVFQ VQTRLLKAIF GPDGSRIPYIEQVSKAMLEL KALESSDLTE VVVYGSYLYK LRTKWMLQSM AEWHRQRQER GMLKLAEAMN ALELGPWMK
• Purity: >85% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: DPPA5 developmental pluripotency associated 5 [ Homo sapiens ]
• Official Symbol: DPPA5
• Synonyms: developmental pluripotency associated 5; 19201; Ensembl:ENSG00000203909; developmental pluripotency-associated 5 protein;embryonal stem cell specific gene 1; ESG1
• Gene ID: 340168
• mRNA Refseq: NM_001025290.2
• Protein Refseq: NP_001020461.1
• MIM: 611111
• UniProt ID: A6NC42
• Chromosome Location: 6q13
• Function: RNA binding