Recombinant Human DERL2, His-tagged

• Cat.No.: DERL2-11941H
• Product Overview: Recombinant Human DERL2 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-70a.a.
• Description: Proteins that are unfolded or misfolded in the endoplasmic reticulum (ER) must be refolded or degraded to maintain the homeostasis of the ER. DERL2 is involved in the degradation of misfolded glycoproteins in the ER (Oda et al., 2006 [PubMed 16449189]).
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: DERL2 Der1-like domain family, member 2 [ Homo sapiens ]
• Official Symbol: DERL2
• Synonyms: DERL2; Der1-like domain family, member 2; derlin-2; CGI 101; derlin 2; F LAN 1; F LANa; FLANa; DERtrin-2; carcinoma related; der1-like protein 2; degradation in endoplasmic reticulum protein 2; F-LANa; CGI-101; F-LAN-1
• Gene ID: 51009
• mRNA Refseq: NM_016041
• Protein Refseq: NP_057125
• MIM: 610304
• UniProt ID: Q9GZP9
• Chromosome Location: 17p13.2
• Pathway: HRD1/SEL1 ERAD complex, organism-specific biosystem; HRD1/SEL1 ERAD complex, conserved biosystem; Protein processing in endoplasmic reticulum, organism-specific biosystem; Protein processing in endoplasmic reticulum, conserved biosystem
• Function: protein binding