Recombinant Human DEFA1 Protein, MYC/DDK-tagged

• Cat.No.: DEFA1-454H
• Product Overview: Recombinant Human DEFA1 fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Description: Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 10 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: DEFA1 defensin, alpha 1 [ Homo sapiens ]
• Official Symbol: DEFA1
• Synonyms: DEFA1; defensin, alpha 1; DEF1, DEFA2, defensin, alpha 1, myeloid related sequence , defensin, alpha 2 , MRS; neutrophil defensin 1; HNP 1; defensin, alpha 2; myeloid-related sequence; defensin, alpha 1, myeloid-related sequence; HP1; MRS; DEF1; HP-1; DEFA2; HNP-1; DEFA1B; MGC138393
• Gene ID: 1667
• mRNA Refseq: NM_004084
• Protein Refseq: NP_004075
• MIM: 125220
• UniProt ID: P59665