Recombinant Human DDX19B, His-tagged

• Cat.No.: DDX19B-11893H
• Product Overview: Recombinant Human DDX19B protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: C-term-370a.a.
• Description: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which exhibits RNA-dependent ATPase and ATP-dependent RNA-unwinding activities. This protein is recruited to the cytoplasmic fibrils of the nuclear pore complex, where it participates in the export of mRNA from the nucleus. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B [ Homo sapiens ]
• Official Symbol: DDX19B
• Synonyms: DDX19B; DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B; DDX19, DEAD (Asp Glu Ala As) box polypeptide 19 , DEAD/H (Asp Glu Ala Asp/His) box polypeptide 19 (Dbp5, yeast, homolog); ATP-dependent RNA helicase DDX19B; DBP5; DEAD-box protein 5; yeast Dbp5 homolog; DEAD box protein 19B; DEAD box RNA helicase DEAD5; DEAD-box RNA helicase DEAD5; ATP-dependent RNA helicase DDX19; DEAD (Asp-Glu-Ala-As) box polypeptide 19B; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 19 (Dbp5, yeast, homolog); RNAh; DDX19
• Gene ID: 11269
• mRNA Refseq: NM_001014449
• Protein Refseq: NP_001014449
• MIM: 605812
• UniProt ID: Q9UMR2
• Chromosome Location: 16q22.3
• Function: ATP binding; ATP-dependent helicase activity; RNA binding; helicase activity; hydrolase activity; nucleotide binding