Recombinant Human DCUN1D2, His-tagged

• Cat.No.: DCUN1D2-3620H
• Product Overview: Recombinant human DCUN1D2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: DCN1-like protein 2, also known as DCUN1D2, which contains one DCUN1 domain and 1 UBA-like domain, may play a role in the neddylation of cullins that regulate SCF-type ubiquitin ligase complexes. The gene encoding Dcun1D2 exists on human chromosome 13. Chromosome 13 houses key tumor suppressor genes, including BRCA2 and RB1, which are associated with breast cancer susceptibility and retinoblastoma, respectively.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT,30% glycerol, 0.1M NaCl
• Molecular Weight: 32.3kDa (279aa),confirmed by MALDI-TOF
• Purity: > 95% by SDS - PAGE
• Concentration: 1 mg/ml (determined by Bradford assay)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MHKLKSSQKD KVRQFMACTQ AGERTAIYCL TQNEWRLDEA TDSFFQNPDS LHRESMRNAV DKKKLERLYGRYKDPQDENK IGVDGIQQFC DDLSLDPASI SVLVIAWKFR AATQCEFSRK EFLDGMTELG CDSMEKLKAL LPRLEQELKD TAKFKDFYQF TFTFAKNPGQ KGLDLEMAVA YWKLVLSGRF KFLDLWNTFL MEHHKRSIPR DTWNLLLDFG NMIADDMSNY DEEGAWPVLI DDFVEYARPVVTGGKRSLF
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2 (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: DCUN1D2
• Synonyms: DCUN1D2; C13orf17; FLJ10704; FLJ20092; DCN1, defective in cullinneddylation 1, domain containing 2 (S. cerevisiae); DCN1-like protein 2; OTTHUMP00000018776; DCUN1 domain-containing protein 2; defective in cullinneddylation protein 1-like protein 2
• Gene ID: 55208
• mRNA Refseq: NM_001014283
• Protein Refseq: NP_001014305
• UniProt ID: Q6PH85
• Chromosome Location: 13q34