Recombinant Human DCK Protein, DDK-tagged

• Cat.No.: DCK-857H
• Product Overview: Recombinant Human DCK fused with DDK tag at C-terminal was expressed in Sf9 cells.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: Flag
• Description: Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.
• Form: 50mM Tris-HCl pH8.0, 150mM NaCl, 20% glycerol. Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
• Molecular Mass: 30 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: DCK deoxycytidine kinase [ Homo sapiens ]
• Official Symbol: DCK
• Synonyms: DCK; deoxycytidine kinase; deoxynucleoside kinase; MGC117410; MGC138632
• Gene ID: 1633
• mRNA Refseq: NM_000788
• Protein Refseq: NP_000779
• MIM: 125450
• UniProt ID: P27707