Recombinant Human DCAMKL2, GST-tagged, Active

• Cat.No.: DCAMKL2-293H
• Product Overview: Recombinant human DCAMKL2 (1-690) was expressed by baculovirus inSf9 insect cellsusing a N-terminal GST tag. MW=105kDa.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST
• Protein Length: 1-690 a.a.
• Description: DCAMKL2 (also known as doublecortin-like kinase 2 or DCLK2) is a close homologue of doublecortin or DCX which is associated with intractable epilepsy in humans, due to a severe disorganization of the neocortex and hippocampus known as classical lissencephaly. DCX; DCLK2-null mice display frequent spontaneous seizures that originate in the hippocampus, with most animals dying in the first few months of life.
• Sequence: 1-690.
• Applications: Kinase Assay, Western Blot.
• Storage And Stability: Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: DCLK2 doublecortin-like kinase 2 [ Homo sapiens ]
• Synonyms: DCLK2; doublecortin-like kinase 2; CL2, CLICK2, DCAMKL2, DCDC3, DCDC3B, DCK2, DKFZp761I032, MGC45428; doublecortin and CaM kinase-like 2; EC 2.7.11.1
• Gene ID: 166614
• mRNA Refseq: NM_001040260
• Protein Refseq: NP_001035350
• MIM: 613166
• UniProt ID: Q8N568
• Chromosome Location: 4q31.23-q31.
• Pathway: Bladder cancer; Pathways in cancer
• Function: ATP binding; nucleotide binding; protein serine/threonine kinase activity transferase activity