Recombinant Human DCAF15 Protein (A2-L600), His/Strep tagged

• Cat.No.: DCAF15-1238H
• Product Overview: Recombinant Human 8His-StrepII-TEV-(GG)-DCAF15(A2-L600 end) Protein was expressed in Insect cell.

Specification

• Species: Human
• Source: Insect Cells
• Tag: His&Strep
• Protein Length: A2-L600
• Description: Substrate-recognition component of the DCX(DCAF15) complex, a cullin-4-RING E3 ubiquitin-protein ligase complex that mediates ubiquitination and degradation of target proteins. The DCX(DCAF15) complex acts as a regulator of the natural killer (NK) cells effector functions, possibly by mediating ubiquitination and degradation of cohesin subunits SMC1A and SMC3. May play a role in the activation of antigen-presenting cells (APC) and their interaction with NK cells.
• Form: Liquid
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: DCAF15 DDB1 and CUL4 associated factor 15 [ Homo sapiens (human) ]
• Official Symbol: DCAF15
• Synonyms: DCAF15; DDB1 and CUL4 associated factor 15; C19orf72; DDB1- and CUL4-associated factor 15
• Gene ID: 90379
• mRNA Refseq: NM_138353
• Protein Refseq: wwwcbilmihov/nuccore/NM_138353
• MIM: 620109
• UniProt ID: Q66K64