Recombinant Human DBR1, His-tagged

• Cat.No.: DBR1-11847H
• Product Overview: Recombinant Human DBR1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 204-544a.a.
• Description: The protein encoded by this gene is an RNA lariat debranching enzyme that hydrolyzes 2-5 prime branched phosphodiester bonds. The encoded protein specifically targets the bonds at the branch point of excised lariat intron RNA, converting them to linear molecules that are then degraded. This protein may also be involved in retroviral replication.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: DBR1 debranching enzyme homolog 1 (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: DBR1
• Synonyms: DBR1; debranching enzyme homolog 1 (S. cerevisiae); debranching enzyme (S. Cerevisiae) homolog 1; lariat debranching enzyme; RNA lariat debranching enzyme
• Gene ID: 51163
• mRNA Refseq: NM_016216
• Protein Refseq: NP_057300
• MIM: 607024
• UniProt ID: Q9UK59
• Chromosome Location: 3q22.3
• Function: RNA lariat debranching enzyme activity; hydrolase activity, acting on ester bonds; metal ion binding