Recombinant Human DBN1 Protein, His-tagged

• Cat.No.: DBN1-672H
• Product Overview: Recombinant Human DBN1(Gly3~Ser134 ) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Gly3~Ser134
• Description: The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene.
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 17.9kDa
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others

Gene Information

• Gene Name: DBN1 drebrin 1 [ Homo sapiens ]
• Official Symbol: DBN1
• Synonyms: DBN1; drebrin 1; D0S117E; drebrin; drebrin E; drebrin-1; drebrin E2; developmentally-regulated brain protein; DKFZp434D064
• Gene ID: 1627
• mRNA Refseq: NM_004395
• Protein Refseq: NP_004386
• MIM: 126660
• UniProt ID: Q16643