Recombinant Human DAO Protein, His-tagged

• Cat.No.: DAO-1307H
• Product Overview: Recombinant Human DAO Protein (Met1-Leu347) with N-His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Met1-Leu347
• Description: This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 39.5 kDa
• Purity: > 97%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: DAO D-amino-acid oxidase [ Homo sapiens (human) ]
• Official Symbol: DAO
• Synonyms: DAO; D-amino-acid oxidase; DAMOX; D-amino acid oxidase; DAAO; OXDA; MGC35381
• Gene ID: 1610
• mRNA Refseq: NM_001917
• Protein Refseq: NP_001908
• MIM: 124050
• UniProt ID: P14920