Recombinant Human DACH2, His-tagged

• Cat.No.: DACH2-11816H
• Product Overview: Recombinant Human DACH2 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 184-313a.a.
• Description: This gene is one of two genes which encode a protein similar to the Drosophila protein dachshund, a transcription factor involved in cell fate determination in the eye, limb and genital disc of the fly. The encoded protein contains two characteristic dachshund domains: an N-terminal domain responsible for DNA binding and a C-terminal domain responsible for protein-protein interactions. This gene is located on the X chromosome and is subject to inactivation by DNA methylation. The encoded protein may be involved in regulation of organogenesis and myogenesis, and may play a role in premature ovarian failure. Multiple transcript variants encoding different isoforms have been found for this gene.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: DACH2 dachshund homolog 2 (Drosophila) [ Homo sapiens ]
• Official Symbol: DACH2
• Synonyms: DACH2; dachshund homolog 2 (Drosophila); dachshund homolog 2; FLJ31391; MGC138545
• Gene ID: 117154
• mRNA Refseq: NM_001139514
• Protein Refseq: NP_001132986
• MIM: 300608
• UniProt ID: Q96NX9
• Chromosome Location: Xq21.3
• Function: DNA binding; nucleotide binding