Recombinant Human CYP2A6 Protein, Flag-tagged

Cat.No. : CYP2A6-01H
Product Overview : Recombinant protein from the full-length sequence of Homo sapiens cytochrome P450 family 2 subfamily A member 6 (CYP2A6) (NM_000762), with a DYKDDDDK tag was expressed in Human Cells.
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Species : Human
Source : Human Cells
Tag : Flag
Description : This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3; however, it has been renamed CYP2A6.
Molecular Mass : 56.3 kDa
Endotoxin : Endotoxin level is < 0.1 ng/μg of protein (<1EU /μg)
Purity : > 90% by SDS-PAGE gel and Coomassie Blue staining
Applications : Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Storage Buffer : Purified protein formulated in a sterile solution of TBS buffer, pH7.4, without any preservatives
Gene Name CYP2A6 cytochrome P450 family 2 subfamily A member 6 [ Homo sapiens (human) ]
Official Symbol CYP2A6
Synonyms CYP2A6; cytochrome P450 family 2 subfamily A member 6; CPA6; CYP2A; CYP2A3; P450PB; CYPIIA6; P450C2A; cytochrome P450 2A6; 1,4-cineole 2-exo-monooxygenase; coumarin 7-hydroxylase; cytochrome P450 IIA3; cytochrome P450(I); cytochrome P450, family 2, subfamily A, polypeptide 6; cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 6; flavoprotein-linked monooxygenase; xenobiotic monooxygenase; EC 1.14.14.1
Gene ID 1548
mRNA Refseq NM_000762
Protein Refseq NP_000753
MIM 122720
UniProt ID P11509

Not For Human Consumption!

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