Recombinant Human CUB domain containing protein 1 Protein, His&Flag&StrepII tagged

• Cat.No.: CDCP1-099H
• Product Overview: Recombinant human CDCP1/CD318 protein (Q9H5V8) (Cys 689-Glu 836) with a Twin strep tag at the N-terminus and both His, Flag tag at the C-terminus was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: Flag&His&Twin Strep
• Protein Length: 689-836aa
• Description: This gene encodes a transmembrane protein which contains three extracellular CUB domains and acts as a substrate for Src family kinases. The protein plays a role in the tyrosine phosphorylation-dependent regulation of cellular events that are involved in tumor invasion and metastasis. Alternative splicing results in multiple transcript variants of this gene. May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.
• Tag: N-Twin strep and C-His&Flag
• Molecular Mass: 23 kDa
• Endotoxin: Less than 1.0 EU/μg by the LAL method.
• Purity: >95% as determined by SDS-PAGE.
• Storage: Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
• Reconstitution: Reconstitute at 250 μg/mL in sterile water.

Gene Information

• Gene Name: CDCP1 CUB domain containing protein 1 [ Homo sapiens (human) ]
• Official Symbol: CDCP1
• Synonyms: CDCP1; CUB domain containing protein 1; CUB domain-containing protein 1; CD318; SIMA135; membrane glycoprotein gp140; transmembrane and associated with src kinases; subtractive immunization M plus HEp3-associated 135 kDa protein; TRASK
• Gene ID: 64866
• mRNA Refseq: NM_022842
• Protein Refseq: NP_073753
• MIM: 611735
• UniProt ID: Q9H5V8