Description :	The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants.
Source :	HEK293
Species :	Human
Tag :	Myc&DDK
Form :	25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass :	85.3 kDa
Purity :	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration :	>50 ug/mL as determined by microplate BCA method

Gene Name	CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa [ Homo sapiens ]
Official Symbol	CTNNB1
Synonyms	armadillo; CTNNB; MRD19
Gene ID	1499
mRNA Refseq	NM_001098209
Protein Refseq	NP_001091679
MIM	116806
UniProt ID	P35222