Recombinant Human CSNK2A1, GST-tagged, Active

• Cat.No.: CSNK2A1-283H
• Product Overview: Recombinant human full-length CK2alpha1 were co-expressed by baculovirus inSf9insect cells using an N-terminal GST tag on both proteins. MW=70 kDa.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST
• Description: CK2α is a serine-threonine protein kinase whose targets include many critical regulators of cellular growth. It is highly expressed in a lymphopro-liferative disease of cattle and in many human cancers. Overexpression of the CK2 catalytic subunit in lymphocytes of transgenic mice leads to T cell lymphoma. The highest CK2α1 activity is found in mouse testicles and brain, followed by spleen, liver, lung, kidney and heart.
• Sequence: Full-length.
• Applications: Kinase Assay, Western Blot.
• Storage And Stability: Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: CSNK2A1 casein kinase 2, alpha 1 polypeptide [ Homo sapiens ]
• Synonyms: CSNK2A1; casein kinase 2, alpha 1 polypeptide; CKII; CK2A1; casein kinase II alpha 1 subunit; protein kinase CK2; CK2 catalytic subunit alpha; EC 2.7.11.1; OTTHUMP00000029925; OTTHUMP00000029926
• Gene ID: 1457
• mRNA Refseq: NM_001895
• Protein Refseq: NP_001886
• UniProt ID: P68400
• Chromosome Location: 20p13
• MIM: 115440
• Pathway: Adherens junction; Tight junction; Wnt signaling pathway
• Function: ATP binding; nucleotide binding; protein N-terminus binding; protein serine/threonine kinase activity; transferase activity