Recombinant Human CSHL1, GST-tagged

• Cat.No.: CSHL1-11623H
• Product Overview: Recombinant Human CSHL1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: C-term-136a.a.
• Description: The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. This particular family member is expressed in placental villi, although it was originally thought to be a pseudogene. In fact, alternative splicing suggests that the majority of the transcripts would be unable to express a secreted protein. Alternatively spliced transcript variants encoding different isoforms have been identified.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CSHL1 chorionic somatomammotropin hormone-like 1 [ Homo sapiens ]
• Official Symbol: CSHL1
• Synonyms: CSHL1; chorionic somatomammotropin hormone-like 1; CSHP1; chorionic somatomammotropin CS 5; CS 5; CSL; hCS L; MGC149868; growth hormone cluster; chorionic somatomammotropin CS-5; CS-5; hCS-L
• Gene ID: 1444
• mRNA Refseq: NM_001318
• Protein Refseq: NP_001309
• MIM: 603515
• UniProt ID: Q14406
• Chromosome Location: 17q22-q24
• Function: hormone activity; metal ion binding