Recombinant Human CSF3, His-tagged

• Cat.No.: CSF3-90H
• Product Overview: Recombinant HumanGranulocyte Colony Stimulating Factor-His Tag produced inE.coliis a single, non-glycosylated, polypeptide chain containing 174 amino acids, fragment (31-204) and having a molecular mass of 18.8 KD with an amino-terminal hexahistidine tag. G-CSF-His is purified by proprietary chromatographic techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 31-204 a.a.
• Description: Granulocyte Colony Stimulating Factor is a growth factor and/or cytokine produced by the endothelium, macrophages and a number of other immune cells. GCSF stimulates the bone marrow to produce granulocytes and also to stimulate the survival, proliferation, differentiation and function of neutrophil granulocyte progenator cells and mature neutrophils.
• Physical Appearance: Sterile Filtered clear solution.
• Purity: Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
• Formulation: Granulocyte Colony Stimulating Factor His is supplied in 1 x PBS and 50% glycerol.
• Stability: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.

Gene Information

• Gene Name: CSF3 colony stimulating factor 3 (granulocyte) [ Homo sapiens ]
• Synonyms: CSF3; colony stimulating factor 3 (granulocyte); GCSF; G-CSF; MGC45931; colony stimulating factor 3; filgrastim; lenograstim; pluripoietin; granulocyte colony stimulating factor; Filgrastim; Lenograstim; OTTHUMP00000164327; Pluripoietin
• Gene ID: 1440
• mRNA Refseq: NM_000759
• Protein Refseq: NP_000750
• MIM: 138970
• UniProt ID: P09919
• Chromosome Location: 17q11.2-q12
• Pathway: Cytokine-cytokine receptor interaction; Hematopoietic cell lineage; Jak-STAT signaling pathway
• Function: cytokine activity; enzyme binding; growth factor activity; granulocyte colony-stimulating factor receptor binding