Recombinant Human CSF2RB, Fc-tagged

• Cat.No.: CSF2RB-29794TH
• Product Overview: Recombinant full length extracellular domain of Human IL3RB fused to the Fc region of Human IgG1 expressed in modified Human 293 cells.

Specification

• Species: Human
• Tag: Fc
• Description: The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP).
• Conjugation: Fc
• Form: Lyophilised:It is recommended that 0.5 ml of sterile phosphate-buffered saline be added to the vial.Following reconstitution short-term storage at 4°C is recommended, with longer-term storage in aliquots at -18 to -20°C. Repeated freeze thawing is not rec
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 10% Trehalose, 1% Human serum albumin, PBS
• Storage: Store at +4°C.
• Sequences of amino acids: Theoretical Sequence:WERSLAGAEETIPLQTLRCYNDYTSHITC RWADTQDAQRLVNVTLIRRVNEDLLEPVSCDLSDDMPW SACPHPRCVPRRCVIPCQSFVVTDVDYFSFQPDRPLGTRLTVTLTQHVQPPEPRDLQISTDQDHFLLTWSVALGSPQS HWLSPGDLEFEVVYKRLQDSWEDAAILLSNTSQATLGP EHLMPSSTYVARVRTRLAPGSRLSGRPSKWSPEVCWDS QPGDEAQPQNLECFFDGAAVLSCSWEVRKEVASSVSFGLFYKPSPDAGEEECSPVLREGLGSLHTRHHCQIPVPDPAT HGQYIVSVQPRRAEKHIKSSVNIQMAPPSLNVTKDGDS YSLRWETMKMRYEHIDHTFEIQYRKDTATWKDSKTETL QNAHSMALPALEPSTRYWARVRVRTSRTGYNGIWSEWSEA RSWDTESVLPMWGSSNTKVDKKVEPKSCDKTHTCPPCP APELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSH EDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVL TVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREP QVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESN GQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNV FSCSVMHEALHNHYTQKSLSLSPGK
• Sequence Similarities: Belongs to the type I cytokine receptor family. Type 4 subfamily.Contains 2 fibronectin type-III domains.
• Full Length: Full L.

Gene Information

• Gene Name: CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) [ Homo sapiens ]
• Official Symbol: CSF2RB
• Synonyms: CSF2RB; colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage); IL3RB; cytokine receptor common subunit beta; CD131; IL5RB
• Gene ID: 1439
• mRNA Refseq: NM_000395
• Protein Refseq: NP_000386
• MIM: 138981
• Uniprot ID: P32927
• Chromosome Location: 22q12.2-q13.1
• Pathway: Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem
• Function: cytokine receptor activity; contributes_to interleukin-3 receptor activity; contributes_to interleukin-5 receptor activity; protein binding; receptor activity