CSF2RB

  • Official Full Name

    colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)

  • Overview

    The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP).

  • Synonyms

    CSF2RB;colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage);IL3RB;cytokine receptor common subunit beta;CD131;IL5RB;GM-CSF/IL-3/IL-5 receptor common beta-chain;GM-CSF/IL-3/IL-5 receptor common beta subunit;colony-stimu

Recombinant Proteins

  • Human
  • Rat
  • Mouse
  • Zebrafish
  • HEK293
  • Insect Cells
  • Wheat Germ
  • Human Cells
  • Mammalian Cells
  • E.coli
  • In Vitro Cell Free System
  • His
  • Non
  • Fc
  • GST
  • Avi
  • DDK
  • Myc
Cat.# Product name Source (Host) Species Tag Protein Length Price
CSF2RB-3177H Active Recombinant Human CSF2RB protein, His-tagged HEK293 Human His Met1-Trp443
CSF2RB-186H Recombinant Human CSF2RB protein, His-tagged Insect Cells Human His
CSF2RB-1972H Recombinant Human CSF2RB Protein Wheat Germ Human Non
CSF2RB-2231H Recombinant Human CSF2RB, Fc tagged Human Cells Human Fc 1-443 a.a.
CSF2RB-29794TH Recombinant Human CSF2RB, Fc-tagged Human Fc Full L.
Csf2rb-32R Recombinant Rat Csf2rb, Fc tagged Human Cells Rat His 1-440 a.a.
CSF2RB-3964M Recombinant Mouse CSF2RB Protein Mammalian Cells Mouse His
CSF2RB-6370Z Recombinant Zebrafish CSF2RB Mammalian Cells Zebrafish His
CSF2RB-7090H Recombinant Human CSF2RB protein, His & GST-tagged E.coli Human GST&His Pro133~Val233
CSF2RB-1137RCL Recombinant Rat CSF2RB cell lysate Human Cells Rat Non
CSF2RB-2235HCL Recombinant Human CSF2RB cell lysate Human Cells Human Non
CSF2RB-022H Recombinant Human CSF2RB Protein, C-His-tagged E.coli Human His
CSF2Rb-1357R Recombinant Rat CSF2Rb protein(Met1-Trp440), hFc-tagged HEK293 Rat Fc Met1-Trp440
CSF2RB-2013M Recombinant Mouse CSF2RB Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
CSF2RB-2013M-B Recombinant Mouse CSF2RB Protein Pre-coupled Magnetic Beads HEK293 Mouse
CSF2RB-2169HF Recombinant Full Length Human CSF2RB Protein In Vitro Cell Free System Human Full L. 897 amino acids
CSF2RB-3347H Recombinant Human CSF2RB Protein, MYC/DDK-tagged HEK293 Human DDK&Myc
CSF2RB-4037H Recombinant Human CSF2RB Protein (Met1-Trp443), C-His tagged Mammalian Cells Human His Met1-Trp443
Csf2rb-855M Recombinant Mouse Csf2rb Protein, His-tagged E.coli Mouse His His23-Trp441
Csf2rb-941M Recombinant Mouse Csf2rb Protein, MYC/DDK-tagged HEK293 Mouse DDK&Myc

    Involved Pathway

    CSF2RB involved in several pathways and played different roles in them. We selected most pathways CSF2RB participated on our site, such as ARMS-mediated activation,Apoptosis,Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with CSF2RB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    ARMS-mediated activation PSMD5,NRG4,DAB2IPB,JAK3,RASGEF1A,PSMD9,SPTBN1,DUSP2,DUSP4,PTPRA
    DAP12 interactions PHB,GRAP2A,NRG2A,CLEC5A,TREM1,FRS3,LCP2A,DUSP1,FGF8B,RASGRP1
    Cytokine-cytokine receptor interaction GM1987,LIFR,TGFBR1B,LEPB,CCL23,FLT1,HGF,IL24,CCL4L1,IL4R
    Cytokine Signaling in Immune system EIF4EB,CRK,JAK3,PRLRB,FGF20A,NRG3,KLB,TRIM14,EIF4A1,PELI2
    Defective CSF2RA causes pulmonary surfactant metabolism dysfunction 4 (SMDP4) SFTPC,CSF2RA,SFTPB
    Axon guidance EZRA,KIF4,SEMA5B,CFL2,PLXNA1,ARPC5,MYL9,EFNB1,SCN9A,PLXNC1
    Apoptosis PRKAR1B,PRKAR2AA,MYD88,IRF2,Gzmg,TRAF2,AIFM1,DBNLA,HIST1H1C,AKT2
    DAP12 signaling WDR83,DUSP7,LCP2A,AGO2,DUSP1,SPRED2,KLB,FGF20A,PEA15,MARK3

    Protein Function

    CSF2RB has several biochemical functions, for example, contributes_to interleukin-3 receptor activity,contributes_to interleukin-5 receptor activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CSF2RB itself. We selected most functions CSF2RB had, and list some proteins which have the same functions with CSF2RB. You can find most of the proteins on our site.

    Function Related Protein
    protein binding COP1,SLC19A2,ZNF26,NUP54,IGF2BP3,GAGE8,RAB18,Casp3,PRKAR1A,ALAS1
    receptor activity ANPEP,NRP2,CADM1B,CADM3,GRIA2A,Siglece,MED1,GFRA1A,GUCY1A3,ANTXR2

    Interacting Protein

    CSF2RB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CSF2RB here. Most of them are supplied by our site. Hope this information will be useful for your research of CSF2RB.

    JAK2;ITGB1;SHC1;PTPN11;CSF2;IL5;PTPN6

    Resources

    Research Area

    T Cell Cytokine Signaling
    CD Antigen (Basophils)
    CSF Receptor
    Other Interleukins & Receptors

    References

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