Recombinant Human Crystallin, Gamma N, His-tagged

• Cat.No.: CRYGN-6944H
• Product Overview: Recombinant human CRYGN protein, fused to His-tag at N-terminus, was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-182aa
• Description: CRYGN belongs to the Crystallins family. Crystallins are divided into alpha, beta and gamma families, and the beta and gamma-crystallins also comprise a superfamily. Crystallins are the major proteins of the vertebrate eye lens, where they maintain the transparency and refractive index of the lens. The CRYGN is differentially regulated after early development, and are involved in cataract formation as a result of either age-related protein degradation or genetic mutation.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol.
• Molecular Mass: 23.1 kDa (206aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMAQRSG KITLYEGKHF TGQKLEVFGD CDNFQDRGFM NRVNSIHVES GAWVCFNHPD FRGQQFILEH GDYPDFFRWN SHSDHMGSCR PVGMHGEHFR LEIFEGCNFT GQCLEFLEDS PFLQSRGWVK NCVNTIKVYG DGAAWSPRSF GAEDFQLSSS LQSDQGPEEA TTKPATTQPP FLTANL
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: CRYGN crystallin, gamma N [ Homo sapiens ]
• Official Symbol: CRYGN
• Synonyms: CRYGN; crystallin, gamma N; gamma-crystallin N; gammaN-crystallin; gamma-N-crystallin; Gamma-N-crystallin
• Gene ID: 155051
• mRNA Refseq: NM_144727
• Protein Refseq: NP_653328
• MIM: 609603
• UniProt ID: Q8WXF5
• Chromosome Location: 7q36.1