Recombinant Human CRYGD, His-tagged

• Cat.No.: CRYGD-3634H
• Product Overview: Recombinant human CRYGD protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques (1-174aa).

Specification

• Cat. No.: CRYGD-3634H
• Description: CRYGD belongs to the beta/gamma-crystallin family. Crystallins are the dominant structural components of the vertebrate eye lens. Mammalian lens crystallins are divided into alpha, beta, and gamma families. Gamma-crystallins have been involved in cataract formation. Defects in CRYGD are a cause of cataract autosomal dominant (ADC), cataract congenital non-nuclear polymorphic autosomal dominant (CCP), cataract congenital cerulean type 3 (CCA3) and cataract crystalline aculeiform (CACA).
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 5mM DTT, 10% glycerol, 200mM NaCl
• Molecular Weight: 22.9kDa (194aa), confirmed by MALDI-TOF
• Purity: > 95% by SDS - PAGE
• Concentration: 1mg/ml (determined by BCA)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MGKITLYEDR GFQGRHYECS SDHPNLQPYL SRCNSARVDS GCWMLYEQPN YSGLQYFLRR GDYADHQQWM GLSDSVRSCR LIPHSGSHRI RLYEREDYRG QMIEFTEDCS CLQDRFRFNE IHSLNVLEGS WVLYELSNYR GRQYLLMPGD YRRYQDWGAT NARVGSLRRV IDFS
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: CRYGD crystallin, gamma D [ Homo sapiens ]
• Official Symbol: CRYGD
• Synonyms: CRYGD; CCP; CACA; CCA3; CRYG4; cry-g-D; crystallin, gamma D; gamma-crystallin D; OTTHUMP00000163871; gamma crystallin 4; gamma-D-crystallin; gamma-crystallin 4; cry-g-D
• Gene ID: 1421
• mRNA Refseq: NM_006891
• Protein Refseq: NP_008822
• MIM: 123690
• UniProt ID: P07320
• Chromosome Location: 2q33-q35
• Function: protein binding; structural constituent of eye lens