Recombinant Human CRKL Protein, MYC/DDK-tagged
| Cat.No. : | CRKL-3324H |
| Product Overview : | Recombinant Human CRKL protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293. |
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| Description : | This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc&DDK |
| Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
| Molecular Mass : | 33.6 kDa |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration : | >50 ug/mL as determined by microplate BCA method |
| Gene Name | CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like [ Homo sapiens ] |
| Official Symbol | CRKL |
| Synonyms | v-crk avian sarcoma virus CT10 oncogene homolog-like; v-crk sarcoma virus CT10 oncogene homolog (avian)-like |
| Gene ID | 1399 |
| mRNA Refseq | NM_005207 |
| Protein Refseq | NP_005198 |
| MIM | 602007 |
| UniProt ID | P46109 |
Not For Human Consumption!
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