Recombinant Human CREB5 protein, His & T7-tagged

• Cat.No.: CREB5-1112H
• Product Overview: Recombinant Human CREB5 aa. (Gln308~Leu508 (Accession # Q02930) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Description: The product of this gene belongs to the CRE (cAMP response element)-binding protein family. Members of this family contain zinc-finger and bZIP DNA-binding domains. The encoded protein specifically binds to CRE as a homodimer or a heterodimer with c-Jun or CRE-BP1, and functions as a CRE-dependent trans-activator. Alternatively spliced transcript variants encoding different isoforms have been identified.
• Source: E. coli
• Species: Human
• Tag: His&T7
• Form: Freeze-dried powder
• Molecular Mass: 31kDa as determined by SDS-PAGE reducing conditions.
• Protein length: Gln308~Leu508
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >90%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
• Reconstitution: Reconstitute in sterile ddH2O.

Gene Information

• Gene Name: CREB5 cAMP responsive element binding protein 5 [ Homo sapiens (human) ]
• Official Symbol: CREB5
• Synonyms: CREB5; cAMP responsive element binding protein 5; CREB-5; CRE-BPA; cyclic AMP-responsive element-binding protein 5; cAMP response element-binding protein CRE-BPa
• Gene ID: 9586
• mRNA Refseq: NM_001011666.2
• Protein Refseq: NP_001011666.1
• UniProt ID: Q02930