Recombinant Human CPSF6, GST-tagged

• Cat.No.: CPSF6-11540H
• Product Overview: Recombinant Human CPSF6 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: The protein encoded by this gene is one subunit of a cleavage factor required for 3 RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3 end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-351a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CPSF6 cleavage and polyadenylation specific factor 6, 68kDa [ Homo sapiens ]
• Official Symbol: CPSF6
• Synonyms: CPSF6; cleavage and polyadenylation specific factor 6, 68kDa; cleavage and polyadenylation specific factor 6, 68kD subunit; cleavage and polyadenylation specificity factor subunit 6; CFIM; CFIM68; HPBRII 4; HPBRII 7; protein HPBRII-4/7; CPSF 68 kDa subunit; pre-mRNA cleavage factor Im (68kD); pre-mRNA cleavage factor I, 68kD subunit; pre-mRNA cleavage factor Im 68 kDa subunit; cleavage and polyadenylation specificity factor 68 kDa subunit; HPBRII-4; HPBRII-7
• Gene ID: 11052
• mRNA Refseq: NM_007007
• Protein Refseq: NP_008938
• MIM: 604979
• UniProt ID: Q16630
• Chromosome Location: 12q15
• Pathway: mRNA surveillance pathway, organism-specific biosystem; mRNA surveillance pathway, conserved biosystem
• Function: contributes_to RNA binding; mRNA binding; nucleotide binding; protein binding