Recombinant Human COP1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: COP1-1483H
• Product Overview: RFWD2 MS Standard C13 and N15-labeled recombinant protein (NP_071902) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: COP1 (COP1 E3 Ubiquitin Ligase) is a Protein Coding gene. Diseases associated with COP1 include Autism. Among its related pathways are Regulation of activated PAK-2p34 by proteasome mediated degradation and Direct p53 effectors. An important paralog of this gene is WDR81.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 80.5 kDa
• AA Sequence: MSGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGGLGGPVRPVLVAPAVSGSGGGAVSTGLSRHSCAARPSAGVGGSSSSLGSGSRKRPLLAPLCNGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNIDHLYPNFLVNELILKQKQRFEEKRFKLDHSVSSTNGHRWQIFQDWLGTDQDNLDLANVNLMLELLVQKKKQLEAESHAAQLQILMEFLKVARRNKREQLEQIQKELSVLEEDIKRVEEMSGLYSPVSEDSTVPQFEAPSPSHSSIIDSTEYSQPPGFSGSSQTKKQPWYNSTLASRRKRLTAHFEDLEQCYFSTRMSRISDDSRTASQLDEFQECLSKFTRYNSVRPLATLSYASDLYNGSSIVSSIEFDRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHYPENEMTCNSKISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRNTKQPIMVFKGHRKAVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHINEKNFVGLASNGDYIACGSENNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVCWRALPDGESNVLIAANSQGTIKVLELVTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: COP1 COP1 E3 ubiquitin ligase [ Homo sapiens (human) ]
• Official Symbol: COP1
• Synonyms: COP1; COP1 E3 ubiquitin ligase; FAP78; RFWD2; CFAP78; RNF200; E3 ubiquitin-protein ligase COP1; E3 ubiquitin-protein ligase RFWD2; RING finger protein 200; RING-type E3 ubiquitin transferase RFWD2; constitutive photomorphogenesis protein 1 homolog; constitutive photomorphogenic protein 1; putative ubiquitin ligase COP1; ring finger and WD repeat domain 2, E3 ubiquitin protein ligase; EC 2.3.2.27
• Gene ID: 64326
• mRNA Refseq: NM_022457
• Protein Refseq: NP_071902
• MIM: 608067
• UniProt ID: Q8NHY2