Recombinant Human Collapsin Response Mediator Protein 1

• Cat.No.: CRMP1-110H
• Product Overview: Recombinant Human Collapsin Response Mediator Protein 1 protein expressed inE.coliencodes 448-568 amino acids and has a molecular mass of 39 kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Protein Length: 448-568 a.a.
• Description: Collapsin response mediator proteins (CRMPs) are cytosolic phosphoproteins involved in neuronal differentiation and axonal guidance. CRMP2 was previously shown to mediate the repulsive effect of Sema3A on axons and to participate in axonal specification. The X-ray crystal structure of murine CRMP1 was determined at 2.1 resolution and demonstrates that CRMP1 is a bilobed 'lung-shaped' protein forming a tetrameric assembly.
• Formulation: Recombinant Human CRMP-1 protein at 100µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
• Application And Suggested Dilutions: •ELISA •Inhibition Assays •Western Blotting.
• Characterization: On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 39 kDa.
• Storage & Stability: Store vial at -200°Cto -800°C. When stored at the recommended temperature, this protein is stable for 12 months.

Gene Information

• Gene Name: CRMP1 collapsin response mediator protein 1 [ Homo sapiens ]
• Synonyms: CRMP1; collapsin response mediator protein 1; DRP1; DRP-1; DPYSL1; Dihydropyrimidinase-related protein 1;CRMP-1; dihydropyrimidinase related protein-1; dihydropyrimidinase-like 1
• Gene ID: 1400
• mRNA Refseq: NM_001014809
• Protein Refseq: NP_001014809
• UniProt ID: Q14194
• Chromosome Location: 4p16.1
• MIM: 602462
• Pathway: Axon guidance
• Function: dihydropyrimidinase activity; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; protein binding