Recombinant Human COL5A1, His-tagged

• Cat.No.: COL5A1-11437H
• Product Overview: Recombinant Human COL5A1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 243-591a.a.
• Description: This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are associated with Ehlers-Danlos syndrome, types I and II.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: COL5A1 collagen, type V, alpha 1 [ Homo sapiens ]
• Official Symbol: COL5A1
• Synonyms: COL5A1; collagen, type V, alpha 1; collagen alpha-1(V) chain; alpha 1 type V collagen
• Gene ID: 1289
• mRNA Refseq: NM_000093
• Protein Refseq: NP_000084
• MIM: 120215
• UniProt ID: P20908
• Chromosome Location: 9q34.2-q34.3
• Pathway: Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; ECM-receptor interaction, organism-specific biosystem; ECM-receptor interaction, conserved biosystem; Focal Adhesion, organism-specific biosystem
• Function: extracellular matrix structural constituent; heparin binding; integrin binding; platelet-derived growth factor binding; proteoglycan binding