Recombinant Human CNTN6, Fc-tagged

• Cat.No.: CNTN6-26744TH
• Product Overview: Recombinant full length Human Contactin 6 fused at the C terminus to the Fc portion of Human IgG; MWt: ~150 kDa.

Specification

• Species: Human
• Source: HEK293
• Tag: Fc
• Protein Length: 999 amino acids
• Description: The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system.
• Conjugation: Fc
• Molecular Weight: 150.000kDa inclusive of tags
• Tissue specificity: Expressed in nervous system. Highly expressed in cerebellum. Expressed at intermediate level in thalamus, subthalamic nucleus. Weakly expressed in corpus callosum, caudate nucleus and spinal cord.
• Biological activity: Induces Hes-1 in 3T3L-1 cells.
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: PBS
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
• Sequence Similarities: Belongs to the immunoglobulin superfamily. Contactin family.Contains 4 fibronectin type-III domains.Contains 6 Ig-like C2-type (immunoglobulin-like) domains.

Gene Information

• Gene Name: CNTN6 contactin 6 [ Homo sapiens ]
• Official Symbol: CNTN6
• Synonyms: CNTN6; contactin 6; contactin-6; NB 3; neural adhesion molecule
• Gene ID: 27255
• mRNA Refseq: NM_014461
• Protein Refseq: NP_055276
• MIM: 607220
• Uniprot ID: Q9UQ52
• Chromosome Location: 3p26-p25
• Pathway: Axon guidance, organism-specific biosystem; CHL1 interactions, organism-specific biosystem; Developmental Biology, organism-specific biosystem; L1CAM interactions, organism-specific biosystem; Notch signaling pathway, organism-specific biosystem