Recombinant Human CNGA3, His-tagged

• Cat.No.: CNGA3-11377H
• Product Overview: Recombinant Human CNGA3 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 590-694a.a.
• Description: This gene encodes a member of the cyclic nucleotide-gated cation channel protein family which is required for normal vision and olfactory signal transduction. Mutations in this gene are associated with achromatopsia (rod monochromacy) and color blindness. Two alternatively spliced transcripts encoding different isoforms have been described.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: CNGA3 cyclic nucleotide gated channel alpha 3 [ Homo sapiens ]
• Official Symbol: CNGA3
• Synonyms: CNGA3; cyclic nucleotide gated channel alpha 3; ACHM2, CNCG3; cyclic nucleotide-gated cation channel alpha-3; CCNC1; CCNCa; CNG3; CNG-3; CNG channel alpha-3; cyclic nucleotide-gated channel alpha-3; cone photoreceptor cGMP-gated channel alpha subunit; cone photoreceptor cGMP-gated channel subunit alpha; ACHM2; CNCG3; CCNCalpha
• Gene ID: 1261
• mRNA Refseq: NM_001079878
• Protein Refseq: NP_001073347
• MIM: 600053
• UniProt ID: Q16281
• Chromosome Location: 2q11.2
• Pathway: Olfactory transduction, organism-specific biosystem; Olfactory transduction, conserved biosystem; Visual signal transduction: Cones, organism-specific biosystem
• Function: cGMP binding; intracellular cyclic nucleotide activated cation channel activity; ion channel activity; ligand-gated ion channel activity; nucleotide binding