Recombinant Human CLK2, GST-tagged

• Cat.No.: CLK2-11334H
• Product Overview: Recombinant Human CLK2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene encodes a member of the CLK family of dual specificity protein kinases. CLK family members have been shown to interact with, and phosphorylate, serine- and arginine-rich (SR) proteins of the spliceosomal complex, which is a part of the regulatory mechanism that enables the SR proteins to control RNA splicing. Note that this gene is distinct from TELO2 gene (GeneID:9894), which shares CLK2 and hCLK2 symbol aliases in common with this gene, but encodes a protein that is involved in telomere length regulation.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: C-term-300a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CLK2 CDC-like kinase 2 [ Homo sapiens ]
• Official Symbol: CLK2
• Synonyms: CLK2; CDC-like kinase 2; dual specificity protein kinase CLK2; clk2; CLK kinase; hCLK2; MGC61500
• Gene ID: 1196
• mRNA Refseq: NM_003993
• Protein Refseq: NP_003984
• MIM: 602989
• UniProt ID: P49760
• Chromosome Location: 1q21
• Pathway: mRNA processing, organism-specific biosystem
• Function: ATP binding; nucleotide binding; protein binding; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; protein tyrosine kinase activity