Recombinant Human CLIC4 protein, His-tagged

Description :	CLIC4 (chloride intracellular channel 4), also known as H1, CLIC4L or MTCLIC, is a 253 amino acid single-pass membrane protein that localizes to both the nucleus and the cytoplasm and contains one GST C-terminal domain. CLIC4 functions as a monomer that is able to form selective ion channels in target proteins, thereby facilitating the transport of chloride and other ions. CLIC4 is thought to play a role in apoptosis and has been shown to translocate to the nucleus under stress conditions.
Source :	E. coli
Species :	Human
Tag :	His
Form :	Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.1M NaCl, 1mM DTT, 10% glycerol
Molecular Mass :	30.9 kDa (273aa) confirmed by MALDI-TOF
AA Sequence :	MGSSHHHHHH SSGLVPRGSHPGTHPPFITF NSEVKTDVNK IEEFLEEVLC PPKYLKLSPK HPESNTAGMD IFAKFSAYIK NSRPEANEAL ERGLLKTLQK LDEYLNSPLP DEIDENSMED IKFSTRKFLD GNEMTLADCN LLPKLHIVKV VAKKYRNFDI PKEMTGIWRY LTNAYSRDEF TNTCPSDKEV EIAYSDVAKR MALSMPLNGL KEEDKEPLIE LFVKAGSDGE SIGNCPFSQR LFMILWLKGV VFSVTTVDLK RKPADLQNLALTK
Purity :	>95% by SDS - PAGE
Storage :	Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
Concentration :	0.5 mg/ml (determined by Bradford assay)
Protein length :	1-253 a.a.

Gene Name	CLIC4 chloride intracellular channel 4 [ Homo sapiens ]
Official Symbol	CLIC4
Synonyms	CLIC4; chloride intracellular channel 4; chloride intracellular channel protein 4; CLIC4L; DKFZP566G223; H1; huH1; p64H1; P64H1; chloride intracellular channel 4 like; intracellular chloride ion channel protein p64H1; MTCLIC; FLJ38640; DKFZp566G223;
Gene ID	25932
mRNA Refseq	NM_013943
Protein Refseq	NP_039234
MIM	606536
UniProt ID	Q9Y696
Chromosome Location	1p36.11
Function	chloride channel activity; protein binding; voltage-gated chloride channel activity; voltage-gated ion channel activity;