Recombinant Human CLDN23, GST-tagged

• Cat.No.: CLDN23-11294H
• Product Overview: Recombinant Human CLDN23 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: C-term-109a.a.
• Description: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed in germinal center B-cells, placenta and stomach as well as in colon tumor. This gene is down-regulated in intestinal type gastric cancer.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CLDN23 claudin 23 [ Homo sapiens ]
• Official Symbol: CLDN23
• Synonyms: CLDN23; claudin 23; claudin-23; CLDNL; 2310014B08Rik; hCG1646163
• Gene ID: 137075
• mRNA Refseq: NM_194284
• Protein Refseq: NP_919260
• MIM: 609203
• UniProt ID: Q96B33
• Chromosome Location: 8p23.1
• Pathway: Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Cell junction organization, organism-specific biosystem; Cell-Cell communication, organism-specific biosystem; Cell-cell junction organization, organism-specific biosystem; Hepatitis C, organism-specific biosystem; Hepatitis C, conserved biosystem
• Function: identical protein binding; structural molecule activity