Recombinant Human CLCF1, Fc-tagged

• Cat.No.: CLCF1-351H
• Product Overview: A DNA sequence encoding the human CLCF1 (NP_037378.1)(Leu28-Phe225) was expressed with the fused Fc region of human IgG1 at the N-terminus.

Specification

• Source: Human Cells
• Species: Human
• Tag: Fc
• Form: Lyophilized from sterile PBS, pH7.4.
• Molecular Mass: The recombinant human CLCF1/Fc is a disulfide-linked homodimer. The reduced monomer comprises 458 amino acids and has a predicted molecular mass of 50.7 kDa. The apparent molecular mass of the protein is approximately 54 kDa in SDS-PAGE under reducing conditions.
• Protein length: Leu28-Phe225
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >85 % as determined by SDS-PAGE
• Stability: Samples are stable for up to twelve months from date of receipt at -70℃
• Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: Hardcopy of COA with reconstitution instruction is sent along with the products.

Gene Information

• Gene Name: CLCF1 cardiotrophin-like cytokine factor 1 [ Homo sapiens ]
• Official Symbol: CLCF1
• Synonyms: CLCF1; cardiotrophin-like cytokine factor 1; CRLF1 associated cytokine like factor 1; B cell stimulating factor 3; BSF 3; BSF3; CISS2; CLC; cold induced sweating syndrome 2; NNT 1; NNT1; novel neurotrophin 1; NR6; novel neurotrophin-1; B-cell stimulating factor 3; B-cell stimulatory factor 3; B-cell-stimulating factor 3; CRLF1 associated cytokine-like factor 1; neurotrophin-1/B-cell stimulating factor-3; BSF-3; NNT-1
• Gene ID: 23529
• mRNA Refseq: NM_001166212
• Protein Refseq: NP_001159684
• MIM: 607672
• UniProt ID: Q9UBD9
• Chromosome Location: 11q13.3
• Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem
• Function: ciliary neurotrophic factor receptor binding; contributes_to ciliary neurotrophic factor receptor binding; contributes_to cytokine activity; cytokine activity; growth factor activity; protein binding; protein heterodimerization activity; receptor binding